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Association of oral frailty and gut microbiota with hypertension cross-sectional results in the Shika study

Association of oral frailty and gut microbiota with hypertension cross-sectional results in the Shika study

 Springer Nature 2025
 Eng
Mô tả biểu ghi
ID:33947
NLM B2
Tác giả CN Nguyễn Thị Thu Thảo
Nhan đề Association of oral frailty and gut microbiota with hypertension: cross-sectional results in the Shika study
Thông tin xuất bản 2025
Thông tin xuất bản Springer Nature
Tóm tắt Although recent studies have reported the association between toxins produced by certain gut microbiota and elevated blood pressure, the relationship between oral frailty (OF) and gut microbiota has rarely been investigated. The purpose of this study was to epidemiologically investigate the relationship between the combination of OF and specific gut microbiota on hypertension in the residents of Shika Town, Ishikawa Prefecture, Japan. A total of 322 residents aged ⩾ 50 years in Shika Town agreed to participate and met the criteria. The OF was evaluated difficulty in chewing and swallowing, oral dryness, number of remaining teeth, and frequency of tooth brushing. Blood pressure was measured using an automatic digital blood pressure meter. Next-generation sequencing was used to analyze the gut microbiota. A two-way analysis of covariance revealed a significant interaction between the two OF groups and the two hypertension groups on Megamonas. The binomial logistic regression analysis stratified by OF revealed a positive correlation between Megamonas and hypertension (OR 1.317; P = 0.023)
Thuật ngữ chủ đề Public health
Từ khóa tự do Megamonas; Gut microbiota
Địa chỉ 100Kho Bài báo quốc tế(1): BQT00036
Tệp tin điện tử https://pubmed.ncbi.nlm.nih.gov/41454073/
Tệp tin điện tử https://lib.hpmu.edu.vn/kiposdata2/tapchi2026/anhbiatc/biabbqt_thumbimage.jpg
MARC
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041[ ] |a Eng
084[ ] |a B2
100[ ] |a Nguyễn Thị Thu Thảo
245[ ] |a Association of oral frailty and gut microbiota with hypertension: cross-sectional results in the Shika study
260[ ] |c 2025
260[ ] |b Springer Nature
520[ ] |a Although recent studies have reported the association between toxins produced by certain gut microbiota and elevated blood pressure, the relationship between oral frailty (OF) and gut microbiota has rarely been investigated. The purpose of this study was to epidemiologically investigate the relationship between the combination of OF and specific gut microbiota on hypertension in the residents of Shika Town, Ishikawa Prefecture, Japan. A total of 322 residents aged ⩾ 50 years in Shika Town agreed to participate and met the criteria. The OF was evaluated difficulty in chewing and swallowing, oral dryness, number of remaining teeth, and frequency of tooth brushing. Blood pressure was measured using an automatic digital blood pressure meter. Next-generation sequencing was used to analyze the gut microbiota. A two-way analysis of covariance revealed a significant interaction between the two OF groups and the two hypertension groups on Megamonas. The binomial logistic regression analysis stratified by OF revealed a positive correlation between Megamonas and hypertension (OR 1.317; P = 0.023)
650[ ] |a Public health
653[ ] |a Megamonas
653[ ] |a Gut microbiota
773[ ] |t Frontier of Medicine
852[ ] |a 100 |b Kho Bài báo quốc tế |j (1): BQT00036
856[ ] |u https://pubmed.ncbi.nlm.nih.gov/41454073/
856[1 ] |u https://lib.hpmu.edu.vn/kiposdata2/tapchi2026/anhbiatc/biabbqt_thumbimage.jpg
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1 BQT00036 1 Kho Bài báo quốc tế
#1 BQT00036
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