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Assessment of a HeliumArgon-Generated Cold Atmospheric Plasma Device’s Safety Utilizing a Pig Model

Assessment of a HeliumArgon-Generated Cold Atmospheric Plasma Device’s Safety Utilizing a Pig Model

 MDPI 2025
 Eng
Mô tả biểu ghi
ID:33955
NLM B16
Tác giả CN Lê Thị Thùy Linh
Nhan đề Assessment of a Helium/Argon-Generated Cold Atmospheric Plasma Device’s Safety Utilizing a Pig Model
Thông tin xuất bản 2025
Thông tin xuất bản MDPI
Tóm tắt This study was performed to evaluate the safety of the PlazMagik device under multiple parameters with different gas resources (helium (He) and argon (Ar) gases) on pig dorsal skin. After application of PlazMagik to the pig’s dorsal skin, temperature and visual assessments were observed immediately and for up to 30 days. All clinical parameters, including body weight and blood serum biochemistry, along with histopathological analysis (H&E, MT, VB, NBTC staining), were monitored pre-application and at 1, 7, 15, and 30 days post-application of the plasma device. Our results confirmed the safety of the machine at low-output energy settings, which showed gentle skin exfoliation but no tissue damage, while high-output settings led to the skin erosion effect, then developing erythema and coagulation.
Thuật ngữ chủ đề Medical technology
Từ khóa tự do Plasma skin therapy; Dual gas plasma device
Địa chỉ 100Kho Bài báo quốc tế(1): BQT00042
Tệp tin điện tử https://www.mdpi.com/1422-0067/26/16/7854
Tệp tin điện tử https://lib.hpmu.edu.vn/kiposdata2/tapchi2026/anhbiatc/biabbqt_thumbimage.jpg
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TagGiá trị
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039[ ] |y 20260513110803 |z phuongntt
041[ ] |a Eng
084[ ] |a B16
100[ ] |a Lê Thị Thùy Linh
245[ ] |a Assessment of a Helium/Argon-Generated Cold Atmospheric Plasma Device’s Safety Utilizing a Pig Model
260[ ] |c 2025
260[ ] |b MDPI
520[ ] |a This study was performed to evaluate the safety of the PlazMagik device under multiple parameters with different gas resources (helium (He) and argon (Ar) gases) on pig dorsal skin. After application of PlazMagik to the pig’s dorsal skin, temperature and visual assessments were observed immediately and for up to 30 days. All clinical parameters, including body weight and blood serum biochemistry, along with histopathological analysis (H&E, MT, VB, NBTC staining), were monitored pre-application and at 1, 7, 15, and 30 days post-application of the plasma device. Our results confirmed the safety of the machine at low-output energy settings, which showed gentle skin exfoliation but no tissue damage, while high-output settings led to the skin erosion effect, then developing erythema and coagulation.
650[ ] |a Medical technology
653[ ] |a Plasma skin therapy
653[ ] |a Dual gas plasma device
773[ ] |t International Journal of Molecular Sciences
852[ ] |a 100 |b Kho Bài báo quốc tế |j (1): BQT00042
856[ ] |u https://www.mdpi.com/1422-0067/26/16/7854
856[1 ] |u https://lib.hpmu.edu.vn/kiposdata2/tapchi2026/anhbiatc/biabbqt_thumbimage.jpg
890[ ] |a 1 |b 0 |c 0 |d 0
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1 BQT00042 1 Kho Bài báo quốc tế
#1 BQT00042
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