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High Efficiency and Safety of Hepatitis C Treatment Among People Who Inject Drugs in Vietnam

High Efficiency and Safety of Hepatitis C Treatment Among People Who Inject Drugs in Vietnam

 Wiley, 2025
 Eng
Mô tả biểu ghi
ID:34002
NLM B2
Tác giả CN Dương Thị Hương
Nhan đề High Efficiency and Safety of Hepatitis C Treatment Among People Who Inject Drugs in Vietnam
Thông tin xuất bản Wiley,2025
Tóm tắt PWID with detectable HCV RNA were referred to three public hospitals for a 12-week regimen of generic sofosbuvir/daclatasvir, with ribavirin if cirrhosis, and with CBO support for referral and adherence. Treatment safety was assessed over the course of treatment and success was measured by sustained virologic response 12 weeks after the end of treatment (SVR12). Of the 1201 PWID screened with detectable HCV RNA, 1021 were enrolled: 96% male, median age 42 years, 45% HIV-infected, 16% with advanced liver fibrosis, 55% currently injecting, and 71.5% on methadone maintenance therapy (MMT). In total, 979 participants started HCV treatment, and 901 of the 924 participants tested at SVR12 (98%) were cured.
Thuật ngữ chủ đề Public health
Từ khóa tự do Hepatitis C; Inject drugs
Địa chỉ 100Kho Bài báo quốc tế(1): BQT00079
Tệp tin điện tử https://onlinelibrary.wiley.com/doi/10.1111/jvh.70090
Tệp tin điện tử https://lib.hpmu.edu.vn/kiposdata2/tapchi2026/anhbiatc/biabbqt_thumbimage.jpg
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041[ ] |a Eng
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100[ ] |a Dương Thị Hương
245[ ] |a High Efficiency and Safety of Hepatitis C Treatment Among People Who Inject Drugs in Vietnam
260[ ] |b Wiley, |c 2025
520[ ] |a PWID with detectable HCV RNA were referred to three public hospitals for a 12-week regimen of generic sofosbuvir/daclatasvir, with ribavirin if cirrhosis, and with CBO support for referral and adherence. Treatment safety was assessed over the course of treatment and success was measured by sustained virologic response 12 weeks after the end of treatment (SVR12). Of the 1201 PWID screened with detectable HCV RNA, 1021 were enrolled: 96% male, median age 42 years, 45% HIV-infected, 16% with advanced liver fibrosis, 55% currently injecting, and 71.5% on methadone maintenance therapy (MMT). In total, 979 participants started HCV treatment, and 901 of the 924 participants tested at SVR12 (98%) were cured.
650[ ] |a Public health
653[ ] |a Hepatitis C
653[ ] |a Inject drugs
691[ ] |a CTĐT Thạc sĩ Y tế công cộng
691[ ] |a CTĐT Tiến sĩ Y tế Công cộng
773[ ] |t Journal of Viral Hepatitis
852[ ] |a 100 |b Kho Bài báo quốc tế |j (1): BQT00079
856[ ] |u https://onlinelibrary.wiley.com/doi/10.1111/jvh.70090
856[1 ] |u https://lib.hpmu.edu.vn/kiposdata2/tapchi2026/anhbiatc/biabbqt_thumbimage.jpg
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