Trung tâm Thông tin - Thư viện Trường Đại học Y Dược Hải Phòng

NLM	C7
Tác giả CN	Trần Thị Liên
Nhan đề	Causative pathogens and predictors of unfavourable outcomes in central nervous system infections in resource-limited settings
Thông tin xuất bản	2025
Tóm tắt	Pathogens were identified in 24% (80/330) of patients, with Mycobacterium tuberculosis, Klebsiella pneumoniae, and Acinetobacter baumannii being the most common. Mortality was 10%, with fungal meningitis and dual infections having the highest rates. Unfavourable outcomes were observed in 57% of patients. The most common pathogens associated with unfavourable outcomes were M. tuberculosis followed by K. pneumoniae, A. baumannii, and HSV-1. Multivariate analysis identified community-onset infection as a protective factor, while a longer duration of illness before admission (≥5 days) and altered mental status on admission were significant predictors for unfavourable outcomes. Furthermore, the timely administration of appropriate empirical therapy was significantly associated with a reduced risk of mortality.
Thuật ngữ chủ đề	Infectious
Từ khóa tự do	Bacterial meningitis; Central nervous system infections
Địa chỉ	100Kho Bài báo quốc tế(1): BQT00090
Tệp tin điện tử	https://www.ijidonline.com/article/S1201-9712(25)00226-7/fulltext
Tệp tin điện tử	https://lib.hpmu.edu.vn/kiposdata2/tapchi2026/anhbiatc/biabbqt_thumbimage.jpg

MARC

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Tag	Giá trị
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002	13
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008	081223s2025 vm\| vie
009	1 0
039	[ ] \|y 20260519095533 \|z phuongntt
041	[ ] \|a Eng
084	[ ] \|a C7
100	[ ] \|a Trần Thị Liên
245	[ ] \|a Causative pathogens and predictors of unfavourable outcomes in central nervous system infections in resource-limited settings
260	[ ] \|c 2025
520	[ ] \|a Pathogens were identified in 24% (80/330) of patients, with Mycobacterium tuberculosis, Klebsiella pneumoniae, and Acinetobacter baumannii being the most common. Mortality was 10%, with fungal meningitis and dual infections having the highest rates. Unfavourable outcomes were observed in 57% of patients. The most common pathogens associated with unfavourable outcomes were M. tuberculosis followed by K. pneumoniae, A. baumannii, and HSV-1. Multivariate analysis identified community-onset infection as a protective factor, while a longer duration of illness before admission (≥5 days) and altered mental status on admission were significant predictors for unfavourable outcomes. Furthermore, the timely administration of appropriate empirical therapy was significantly associated with a reduced risk of mortality.
650	[ ] \|a Infectious
653	[ ] \|a Bacterial meningitis
653	[ ] \|a Central nervous system infections
691	[ ] \|a CTĐT Bác sĩ nội trú Nội khoa
691	[ ] \|a CTĐT Y khoa - Chính quy
773	[ ] \|t National Library of Medicine
852	[ ] \|a 100 \|b Kho Bài báo quốc tế \|j (1): BQT00090
856	[ ] \|u https://www.ijidonline.com/article/S1201-9712(25)00226-7/fulltext
856	[1 ] \|u https://lib.hpmu.edu.vn/kiposdata2/tapchi2026/anhbiatc/biabbqt_thumbimage.jpg
890	[ ] \|a 1 \|b 0 \|c 0 \|d 0

Dòng	Mã vạch	Bản sao	Nơi lưu	Tình trạng	Cho phép yêu cầu
1	BQT00090	1	Kho Bài báo quốc tế
#1 BQT00090 Nơi lưu Kho Bài báo quốc tế Tình trạng

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