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The correlation between anti-desmoglein autoantibody titers, IgG antibody levels, and the Pemphigus Disease Area Index by location in patients with Pemphigus Vulgaris

The correlation between anti-desmoglein autoantibody titers, IgG antibody levels, and the Pemphigus Disease Area Index by location in patients with Pemphigus Vulgaris

 Quách Thị Hà Giang
 Pakistan Association of Dermatologists 2025
 Eng
DermatologyDesmoglein 1Indirect immunofluorescence
Mô tả biểu ghi
ID:34031
NLM C21
Tác giả CN Quách Thị Hà Giang
Nhan đề The correlation between anti-desmoglein autoantibody titers, IgG antibody levels, and the Pemphigus Disease Area Index by location in patients with Pemphigus Vulgaris
Thông tin xuất bản 2025
Thông tin xuất bản Pakistan Association of Dermatologists
Tóm tắt Among 48 patients (mean age 56.15 years; 64.58% female), anti-Dsg1 positivity was 91.67%, and anti-Dsg3 positivity was 66.67%. Anti-Dsg1 positivity was significantly higher in patients with cutaneous lesions (97.73% vs. 25.00%; P=0.0009), while anti-Dsg3 positivity was higher in those with mucosal lesions (92.86% vs. 30.00%; P<0.0001). Anti-Dsg1 levels correlated with cutaneous PDAI (r=0.378; P=0.0081), and anti-Dsg3 levels strongly correlated with mucosal PDAI (r=0.795; P<0.0001). IIF titers correlated with total PDAI (r=0.377; P=0.0082) and mucosal PDAI (r=0.389; P=0.0062), and were associated with anti-Dsg3 levels (r=0.444; P=0.0015). Higher anti-Dsg1 levels were observed in IIF-negative patients compared to IIF-positive ones. Serum levels of anti-Dsg3 were higher in the IIF-positive group compared to the IIF-negative group (median 114.63 RU/ml vs. 13.9 RU/ml, P=0.0369).
Thuật ngữ chủ đề Dermatology
Từ khóa tự do Desmoglein 1; Indirect immunofluorescence
Địa chỉ 100Kho Bài báo quốc tế(1): BQT00106
Tệp tin điện tử https://www.jpad.com.pk/index.php/jpad/article/view/2867
Tệp tin điện tử https://lib.hpmu.edu.vn/kiposdata2/tapchi2026/anhbiatc/biabbqt_thumbimage.jpg
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039[ ] |y 20260520094008 |z phuongntt
041[ ] |a Eng
084[ ] |a C21
100[ ] |a Quách Thị Hà Giang
245[ ] |a The correlation between anti-desmoglein autoantibody titers, IgG antibody levels, and the Pemphigus Disease Area Index by location in patients with Pemphigus Vulgaris
260[ ] |c 2025
260[ ] |b Pakistan Association of Dermatologists
520[ ] |a Among 48 patients (mean age 56.15 years; 64.58% female), anti-Dsg1 positivity was 91.67%, and anti-Dsg3 positivity was 66.67%. Anti-Dsg1 positivity was significantly higher in patients with cutaneous lesions (97.73% vs. 25.00%; P=0.0009), while anti-Dsg3 positivity was higher in those with mucosal lesions (92.86% vs. 30.00%; P<0.0001). Anti-Dsg1 levels correlated with cutaneous PDAI (r=0.378; P=0.0081), and anti-Dsg3 levels strongly correlated with mucosal PDAI (r=0.795; P<0.0001). IIF titers correlated with total PDAI (r=0.377; P=0.0082) and mucosal PDAI (r=0.389; P=0.0062), and were associated with anti-Dsg3 levels (r=0.444; P=0.0015). Higher anti-Dsg1 levels were observed in IIF-negative patients compared to IIF-positive ones. Serum levels of anti-Dsg3 were higher in the IIF-positive group compared to the IIF-negative group (median 114.63 RU/ml vs. 13.9 RU/ml, P=0.0369).
650[ ] |a Dermatology
653[ ] |a Desmoglein 1
653[ ] |a Indirect immunofluorescence
691[ ] |a CTĐT Bác sĩ nội trú Da liễu
773[ ] |t Journal of Pakistan Association of Dermatologists
852[ ] |a 100 |b Kho Bài báo quốc tế |j (1): BQT00106
856[ ] |u https://www.jpad.com.pk/index.php/jpad/article/view/2867
856[1 ] |u https://lib.hpmu.edu.vn/kiposdata2/tapchi2026/anhbiatc/biabbqt_thumbimage.jpg
890[ ] |a 1 |b 0 |c 0 |d 0
Dòng Mã vạch Bản sao Nơi lưu Tình trạng Cho phép yêu cầu
1 BQT00106 1 Kho Bài báo quốc tế
#1 BQT00106
Nơi lưu Kho Bài báo quốc tế
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