Trung tâm Thông tin - Thư viện Trường Đại học Y Dược Hải Phòng

NLM	C22
Tác giả CN	Phan Hữu Phúc
Nhan đề	Comparison of methylprednisolone alone versus intravenous immunoglobulin plus methylprednisolone for multisystem inflammatory syndrome in children (MIS-C)
Thông tin xuất bản	2025
Thông tin xuất bản	BMJ
Tóm tắt	We included 391 patients, comprising 255 boys and 136 girls, who fulfilled the MIS-C case definition of the US Centers for Disease Control and Prevention. Most patients (80.8%) received intravenous methylprednisolone monotherapy, and 19.2% were administered IVIG in addition to methylprednisolone. In general, the laboratory values indicative of hyperinflammatory and hyperthrombotic states displayed significant early response within 2–3 days after initial treatment, including white cell count (SE=1.77, p<0.001), NEU (SE=0.76, p=0.03), C reactive protein (SE=−46.51, p<0.001), PLT (SE=38.05, p=0.002), fibrinogen (SE=−0.37, p=0.002), d-dimer (SE=−849.8, p=0.02)); while subsequent improvement in cardiac markers was also observed, with pro-B-type natriuretic peptide (SE=−165.2, p<0.001) on day 5 and troponin I (SE=−0.05, p=0.004) on day 7. After propensity score weighting, there were 41 patients in each treatment group. Notably, there were no significant differences in the incidence of cardiac events between treatment groups regarding left ventricular dysfunction and coronary artery dilation or aneurysms (10.3% vs 20.7%, p=0.074 and 63.4% vs 56.1%, p=0.653, respectively)
Thuật ngữ chủ đề	Pediatric
Từ khóa tự do	Multisystem inflammatory syndrome; children
Địa chỉ	100Kho Bài báo quốc tế(1): BQT00124
Tệp tin điện tử	https://doi.org/10.1136/bmjpo-2024-003148
Tệp tin điện tử	https://lib.hpmu.edu.vn/kiposdata2/tapchi2026/anhbiatc/biabbqt_thumbimage.jpg

MARC

Hiển thị đầy đủ trường & trường con

Tag	Giá trị
000	00000nab#a2200000ui#4500
001	34054
002	13
004	B8255314-BEBA-4EAD-9EF6-ED3413536B2C
005	202605201445
008	081223s2025 vm\| vie
009	1 0
039	[ ] \|y 20260520144557 \|z phuongntt
041	[ ] \|a Eng
084	[ ] \|a C22
100	[ ] \|a Phan Hữu Phúc
245	[ ] \|a Comparison of methylprednisolone alone versus intravenous immunoglobulin plus methylprednisolone for multisystem inflammatory syndrome in children (MIS-C)
260	[ ] \|c 2025
260	[ ] \|b BMJ
520	[ ] \|a We included 391 patients, comprising 255 boys and 136 girls, who fulfilled the MIS-C case definition of the US Centers for Disease Control and Prevention. Most patients (80.8%) received intravenous methylprednisolone monotherapy, and 19.2% were administered IVIG in addition to methylprednisolone. In general, the laboratory values indicative of hyperinflammatory and hyperthrombotic states displayed significant early response within 2–3 days after initial treatment, including white cell count (SE=1.77, p<0.001), NEU (SE=0.76, p=0.03), C reactive protein (SE=−46.51, p<0.001), PLT (SE=38.05, p=0.002), fibrinogen (SE=−0.37, p=0.002), d-dimer (SE=−849.8, p=0.02)); while subsequent improvement in cardiac markers was also observed, with pro-B-type natriuretic peptide (SE=−165.2, p<0.001) on day 5 and troponin I (SE=−0.05, p=0.004) on day 7. After propensity score weighting, there were 41 patients in each treatment group. Notably, there were no significant differences in the incidence of cardiac events between treatment groups regarding left ventricular dysfunction and coronary artery dilation or aneurysms (10.3% vs 20.7%, p=0.074 and 63.4% vs 56.1%, p=0.653, respectively)
650	[ ] \|a Pediatric
653	[ ] \|a Multisystem inflammatory syndrome
653	[ ] \|a children
691	[ ] \|a CTĐT Tiến sĩ Nhi khoa
691	[ ] \|a CTĐT Bác sĩ nội trú Nhi khoa
773	[ ] \|t BMJ Paediatr Open
852	[ ] \|a 100 \|b Kho Bài báo quốc tế \|j (1): BQT00124
856	[ ] \|u https://doi.org/10.1136/bmjpo-2024-003148
856	[1 ] \|u https://lib.hpmu.edu.vn/kiposdata2/tapchi2026/anhbiatc/biabbqt_thumbimage.jpg
890	[ ] \|a 1 \|b 0 \|c 0 \|d 0

Dòng	Mã vạch	Bản sao	Nơi lưu	Tình trạng	Cho phép yêu cầu
1	BQT00124	1	Kho Bài báo quốc tế
#1 BQT00124 Nơi lưu Kho Bài báo quốc tế Tình trạng

Bình luận