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Relationship Between PAPP-A Levels in the First Trimester of Pregnancy and Complication Risk

Relationship Between PAPP-A Levels in the First Trimester of Pregnancy and Complication Risk

 Nguyễn Thị Hoàng Trang
 International Journal of women's health
 Dove Medical Press 2025
 Eng
GynecologyFetal growth restrictionHypertensive disorders in pregnancy
Mô tả biểu ghi
ID:34059
NLM C20
Tác giả CN Nguyễn Thị Hoàng Trang
Nhan đề Relationship Between PAPP-A Levels in the First Trimester of Pregnancy and Complication Risk
Thông tin xuất bản 2025
Thông tin xuất bản Dove Medical Press
Tóm tắt Among the 606 participants, 86 (14.2%) presented with low PAPP-A levels (< 0.5 multiple of the median (MoM)), of whom 50 (58.1%) experienced pregnancy complications. A significant association was observed between low PAPP-A levels and hypertensive disorders, fetal growth restriction, spontaneous preterm birth, and miscarriage (OR: 5.1 [95% CI: 2.8-9.4]; 2.54 [1.38-4.68]; 7.48 [3.07-18.21]; and 4.5 [1.4-14.6], respectively). Multivariate regression analysis revealed a significant independent association between PAPP-A levels and these complications (OR: 5.05 [95% CI: 2.71-9.42], 2.52 [1.36-4.66], 7.76 [3.16-19.07], and 4.06 [1.17-14.11], respectively).
Thuật ngữ chủ đề Gynecology
Từ khóa tự do Fetal growth restriction; Hypertensive disorders in pregnancy
Địa chỉ 100Kho Bài báo quốc tế(1): BQT00129
Tệp tin điện tử https://pubmed.ncbi.nlm.nih.gov/41395120/
Tệp tin điện tử https://lib.hpmu.edu.vn/kiposdata2/tapchi2026/anhbiatc/biabbqt_thumbimage.jpg
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041[ ] |a Eng
084[ ] |a C20
100[ ] |a Nguyễn Thị Hoàng Trang
245[ ] |a Relationship Between PAPP-A Levels in the First Trimester of Pregnancy and Complication Risk
260[ ] |c 2025
260[ ] |b Dove Medical Press
520[ ] |a Among the 606 participants, 86 (14.2%) presented with low PAPP-A levels (< 0.5 multiple of the median (MoM)), of whom 50 (58.1%) experienced pregnancy complications. A significant association was observed between low PAPP-A levels and hypertensive disorders, fetal growth restriction, spontaneous preterm birth, and miscarriage (OR: 5.1 [95% CI: 2.8-9.4]; 2.54 [1.38-4.68]; 7.48 [3.07-18.21]; and 4.5 [1.4-14.6], respectively). Multivariate regression analysis revealed a significant independent association between PAPP-A levels and these complications (OR: 5.05 [95% CI: 2.71-9.42], 2.52 [1.36-4.66], 7.76 [3.16-19.07], and 4.06 [1.17-14.11], respectively).
650[ ] |a Gynecology
653[ ] |a Fetal growth restriction
653[ ] |a Hypertensive disorders in pregnancy
691[ ] |a CTĐT Bác sĩ nội trú Sản phụ khoa
773[ ] |t International Journal of women's health
852[ ] |a 100 |b Kho Bài báo quốc tế |j (1): BQT00129
856[ ] |u https://pubmed.ncbi.nlm.nih.gov/41395120/
856[1 ] |u https://lib.hpmu.edu.vn/kiposdata2/tapchi2026/anhbiatc/biabbqt_thumbimage.jpg
890[ ] |a 1 |b 0 |c 0 |d 0
Dòng Mã vạch Bản sao Nơi lưu Tình trạng Cho phép yêu cầu
1 BQT00129 1 Kho Bài báo quốc tế
#1 BQT00129
Nơi lưu Kho Bài báo quốc tế
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