Trung tâm Thông tin - Thư viện Trường Đại học Y Dược Hải Phòng

NLM	C19
Tác giả CN	Đỗ Minh Tùng
Nhan đề	Safety and efficacy of extravascular renal denervation using HyperQure™ renal denervation system in short-term swine model of hypertension
Thông tin xuất bản	Taylor & Francis,2025
Tóm tắt	This study investigated the safety and efficacy of the HyperQure™ extravascular renal denervation (RDN) system in a swine model of mild hypertension. Ten female pigs were fed a 3% salt diet to induce hypertension and underwent either extravascular RDN using the HyperQure™ RDN system (n = 7) or a sham procedure (n = 3). Blood pressure (BP) was continuously monitored using implanted transmitters, and safety assessments were conducted via computed tomography angiography (CTA) at 28 days post-procedure. The primary endpoint was the change in systolic blood pressure (SBP) at four weeks, while secondary endpoints included changes in diastolic BP (DBP), mean arterial pressure (MAP), and histological evaluation of renal nerve and artery integrity. At four weeks, SBP decreased by 11.8 ± 5.2 mmHg in the RDN group compared to an increase of 6.4 ± 4.2 mmHg in controls, resulting in a mean difference of 18.2 mmHg (p < .05). Similar improvements were observed in DBP and MAP, with mean differences of 15.4 and 16.2 mmHg, respectively (both p < .05). CTA revealed no significant renal artery or intraperitoneal organ injury
Thuật ngữ chủ đề	Surgery
Từ khóa tự do	Blood pressure; Hypertension
Địa chỉ	100Bài báo quốc tế(1): BQT00016
Tệp tin điện tử	https://pubmed.ncbi.nlm.nih.gov/40040356/
Tệp tin điện tử	https://lib.hpmu.edu.vn/kiposdata2/tapchi2026/anhbiatc/biabbqt_thumbimage.jpg

MARC

Hiển thị đầy đủ trường & trường con

Tag	Giá trị
000	00000nab#a2200000ui#4500
001	33919
002	13
004	73143AAB-E744-46C6-B336-436D0CAAC01D
005	202605111521
008	081223s2025 vm\| vie
009	1 0
039	[ ] \|a 20260511152145 \|b phuongntt \|y 20260507201212 \|z phuongntt
041	[ ] \|a Eng
084	[ ] \|a C19
100	[ ] \|a Đỗ Minh Tùng
245	[ ] \|a Safety and efficacy of extravascular renal denervation using HyperQure™ renal denervation system in short-term swine model of hypertension
260	[ ] \|b Taylor & Francis, \|c 2025
520	[ ] \|a This study investigated the safety and efficacy of the HyperQure™ extravascular renal denervation (RDN) system in a swine model of mild hypertension. Ten female pigs were fed a 3% salt diet to induce hypertension and underwent either extravascular RDN using the HyperQure™ RDN system (n = 7) or a sham procedure (n = 3). Blood pressure (BP) was continuously monitored using implanted transmitters, and safety assessments were conducted via computed tomography angiography (CTA) at 28 days post-procedure. The primary endpoint was the change in systolic blood pressure (SBP) at four weeks, while secondary endpoints included changes in diastolic BP (DBP), mean arterial pressure (MAP), and histological evaluation of renal nerve and artery integrity. At four weeks, SBP decreased by 11.8 ± 5.2 mmHg in the RDN group compared to an increase of 6.4 ± 4.2 mmHg in controls, resulting in a mean difference of 18.2 mmHg (p < .05). Similar improvements were observed in DBP and MAP, with mean differences of 15.4 and 16.2 mmHg, respectively (both p < .05). CTA revealed no significant renal artery or intraperitoneal organ injury
650	[ ] \|a Surgery
653	[ ] \|a Blood pressure
653	[ ] \|a Hypertension
773	[ ] \|t Clinical and Experimental Hypertension
852	[ ] \|a 100 \|b Bài báo quốc tế \|j (1): BQT00016
856	[ ] \|u https://pubmed.ncbi.nlm.nih.gov/40040356/
856	[1 ] \|u https://lib.hpmu.edu.vn/kiposdata2/tapchi2026/anhbiatc/biabbqt_thumbimage.jpg
890	[ ] \|a 1 \|b 0 \|c 0 \|d 0

Dòng	Mã vạch	Bản sao	Nơi lưu	Tình trạng	Cho phép yêu cầu
1	BQT00016	1	Kho Bài báo quốc tế
#1 BQT00016 Nơi lưu Kho Bài báo quốc tế Tình trạng

Bình luận