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Potential Protective Effect of Hepatitis B Immunity Against Diabetes Mellitus A Retrospective Propensity-Matched Cohort Study

Potential Protective Effect of Hepatitis B Immunity Against Diabetes Mellitus A Retrospective Propensity-Matched Cohort Study

 MDPI, 2025
 Eng
Mô tả biểu ghi
ID:34007
NLM C5
Tác giả CN Hoàng Đình Khánh
Nhan đề Potential Protective Effect of Hepatitis B Immunity Against Diabetes Mellitus: A Retrospective Propensity-Matched Cohort Study
Thông tin xuất bản MDPI,2025
Tóm tắt The HBV-immunized group had a 15% lower diabetes risk than the HBV-unimmunized group (HR: 0.85 [0.84–0.87]). A dose–response effect was observed, with higher HBsAb levels showing a greater reduction in the risk of diabetes. HBsAb levels of ≥100 and ≥1000 mIU/mL were associated with 19% (HR: 0.81 [0.80–0.83]) and 43% (HR: 0.57 [0.54–0.60]) reductions in diabetes risk, respectively, compared with HBsAb < 10 mIU/mL. The reduced risk of diabetes was associated with age. Immunized individuals aged 18 to 44 years, 45 to 64 years, and ≥65 years had 20% (HR: 0.80 [0.78–0.82]), 11% (HR: 0.89 [0.87–0.92]), and 12% (HR: 0.88 [0.84–0.91]) lower diabetes risks, respectively, compared with unimmunized individuals.
Thuật ngữ chủ đề Internal medicine
Từ khóa tự do Hepatitis B; Diabetes
Địa chỉ 100Kho Bài báo quốc tế(1): BQT00084
Tệp tin điện tử https://doi.org/10.3390/diagnostics15131610
Tệp tin điện tử https://lib.hpmu.edu.vn/kiposdata2/tapchi2026/anhbiatc/biabbqt_thumbimage.jpg
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041[ ] |a Eng
084[ ] |a C5
100[ ] |a Hoàng Đình Khánh
245[ ] |a Potential Protective Effect of Hepatitis B Immunity Against Diabetes Mellitus: A Retrospective Propensity-Matched Cohort Study
260[ ] |b MDPI, |c 2025
520[ ] |a The HBV-immunized group had a 15% lower diabetes risk than the HBV-unimmunized group (HR: 0.85 [0.84–0.87]). A dose–response effect was observed, with higher HBsAb levels showing a greater reduction in the risk of diabetes. HBsAb levels of ≥100 and ≥1000 mIU/mL were associated with 19% (HR: 0.81 [0.80–0.83]) and 43% (HR: 0.57 [0.54–0.60]) reductions in diabetes risk, respectively, compared with HBsAb < 10 mIU/mL. The reduced risk of diabetes was associated with age. Immunized individuals aged 18 to 44 years, 45 to 64 years, and ≥65 years had 20% (HR: 0.80 [0.78–0.82]), 11% (HR: 0.89 [0.87–0.92]), and 12% (HR: 0.88 [0.84–0.91]) lower diabetes risks, respectively, compared with unimmunized individuals.
650[ ] |a Internal medicine
653[ ] |a Hepatitis B
653[ ] |a Diabetes
691[ ] |a CTĐT Thạc sĩ Nội khoa
691[ ] |a CTĐT Tiến sĩ Nội khoa
773[ ] |t Diagnostics
852[ ] |a 100 |b Kho Bài báo quốc tế |j (1): BQT00084
856[ ] |u https://doi.org/10.3390/diagnostics15131610
856[1 ] |u https://lib.hpmu.edu.vn/kiposdata2/tapchi2026/anhbiatc/biabbqt_thumbimage.jpg
890[ ] |a 1 |b 0 |c 0 |d 0
Dòng Mã vạch Bản sao Nơi lưu Tình trạng Cho phép yêu cầu
1 BQT00084 1 Kho Bài báo quốc tế
#1 BQT00084
Nơi lưu Kho Bài báo quốc tế
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