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Ninjin’yoeito for Impaired Oral Function in Older Adults A Prospective, Open-Label Pilot Study

Ninjin’yoeito for Impaired Oral Function in Older Adults A Prospective, Open-Label Pilot Study

 MDPI 2025
 Eng
Mô tả biểu ghi
ID:34041
NLM C29
Tác giả CN Ngô Quang Trung
Nhan đề Ninjin’yoeito for Impaired Oral Function in Older Adults: A Prospective, Open-Label Pilot Study
Thông tin xuất bản 2025
Thông tin xuất bản MDPI
Tóm tắt Symptom scores decreased from 8.27 at baseline to 3.64 at 12 weeks (p = 0.006), while oral condition scores improved from 5.09 to 1.36 (p = 0.006). Mucosal moisture increased (25.1 to 28.1, p = 0.03), and RSST frequency improved (2.18 to 4.55, p = 0.046). Questionnaire scores declined from 5.1 to 2.0 (p < 0.001). VAS-taste was unchanged overall (p = 0.21) but improved in low baseline patients. Laboratory findings showed no adverse changes, with favorable lipid trends. Immune analysis revealed a decline in NKG2D expression (p = 0.02), whereas other activating and inhibitory markers remained stable.
Thuật ngữ chủ đề Traditional medicine
Từ khóa tự do Kampo medicine; Traditional Japanese medicine
Địa chỉ 100Kho Bài báo quốc tế(1): BQT00114
Tệp tin điện tử https://www.mdpi.com/1648-9144/62/1/48
Tệp tin điện tử https://lib.hpmu.edu.vn/kiposdata2/tapchi2026/anhbiatc/biabbqt_thumbimage.jpg
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041[ ] |a Eng
084[ ] |a C29
100[ ] |a Ngô Quang Trung
245[ ] |a Ninjin’yoeito for Impaired Oral Function in Older Adults: A Prospective, Open-Label Pilot Study
260[ ] |c 2025
260[ ] |b MDPI
520[ ] |a Symptom scores decreased from 8.27 at baseline to 3.64 at 12 weeks (p = 0.006), while oral condition scores improved from 5.09 to 1.36 (p = 0.006). Mucosal moisture increased (25.1 to 28.1, p = 0.03), and RSST frequency improved (2.18 to 4.55, p = 0.046). Questionnaire scores declined from 5.1 to 2.0 (p < 0.001). VAS-taste was unchanged overall (p = 0.21) but improved in low baseline patients. Laboratory findings showed no adverse changes, with favorable lipid trends. Immune analysis revealed a decline in NKG2D expression (p = 0.02), whereas other activating and inhibitory markers remained stable.
650[ ] |a Traditional medicine
653[ ] |a Kampo medicine
653[ ] |a Traditional Japanese medicine
691[ ] |a CTĐT Bác sĩ Y học cổ truyền
691[ ] |a CTĐT Bác sĩ nội trú Y học cổ truyền
773[ ] |t Medicina
852[ ] |a 100 |b Kho Bài báo quốc tế |j (1): BQT00114
856[ ] |u https://www.mdpi.com/1648-9144/62/1/48
856[1 ] |u https://lib.hpmu.edu.vn/kiposdata2/tapchi2026/anhbiatc/biabbqt_thumbimage.jpg
890[ ] |a 1 |b 0 |c 0 |d 0
Dòng Mã vạch Bản sao Nơi lưu Tình trạng Cho phép yêu cầu
1 BQT00114 1 Kho Bài báo quốc tế
#1 BQT00114
Nơi lưu Kho Bài báo quốc tế
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